Endocare Renewal Retinol Intensive Serum, thanks to its anhydrous texture formulated with RetinSphere® Technology, contains a high concentration of retinoids in microsponges that provide effective epidermal retexturization and renewal. Visibly reduces fine lines and wrinkles and unifies skin texture, thus improving its appearance and luminosity. Tested under dermatological control. Non comedogenic. For whom it is indicated: Serum treatment indicated for all skin types. Instructions for use: Apply at night to clean facial skin progressively and as tolerated according to the Renewal regimen or your prescriber's instructions. Avoid sun exposure or use photoprotection. Avoid direct contact with eyes and mucous membranes. Precautions: Shake before use. External use. Avoid contact with eyes and mucous membranes. A slight stinging and peeling is normal in the first applications. In case of continued irritation, suspend the application. A color change does not affect its effectiveness.