After 50, most men begin to notice changes in urination: the urine stream becomes weaker, they feel the urge to urinate more often, they have to get up one or more times a night to urinate... they are clear signs that the prostate is requiring special care such as Opti +50 Prostaplus. How to use: Take 1 tablet a day, without chewing and accompanied by 1 or 2 large glasses of water.