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Prodefen Plus 10 Sachets. Prodefen is a dietary supplement containing fructooligosaccharides (also known as prebiotics) and seven strains of microorganisms (probiotics) that naturally inhabit the digestive system. Prodefen includes the specific strain for children called Bifidobacterium Infantis, which is commonly found in the intestinal tract of children. Probiotics are microorganisms that, when kept alive and active, and administered in adequate quantities, provide benefits to the individual who ingests them. Prodefen can be used in children of any age as it includes specific microorganisms for children.